Total Commander is a legend. Originally released as Windows Commander in 1993, it's been the go-to file manager for Windows power users for over 30 years. It has a devoted following, a massive plugin ecosystem, and a keyboard-driven workflow that its fans swear by. If you've ever seen someone navigate their entire file system without touching a mouse, there's a good chance they were using Total Commander.
FTPie is a much newer tool with a different focus. It's a file manager too — with the same dual-pane layout that Total Commander popularized — but built specifically around FTP and cloud storage, with modern UI conventions and a bunch of built-in tools.
Comparing these two isn't entirely fair, because they have different primary purposes. Total Commander is a general-purpose file manager that happens to include FTP. FTPie is an FTP and cloud manager that happens to be a file manager. But since people often consider one as an alternative to the other, let's look at where each one shines.